ABSTRACT
Objective To preliminarily study the use of indocyanine green in hepatic alveolar echinococcosis surgery.Methods The data of 13 patients with hepatic alveolar ecbinococcosis treated at the Affiliated Hospital of Qinghai University from May 2017 to May 2018 with laparotomy and intraoperative indocyanine green injection were retrospectively studied.Images were collected by the fluorescence acquisition system.Results There were 7 females and 6 males,with an average age of (37.9±14.7) years.The mean weight was (57.4±11.3) kg.Except for one patient of Han nationality,the rest were Tibetans.The lesions were not visualized but normal liver tissues emitted green fluorescence.One patient had a slightly enhanced fluorescence circle around the lesion.The fluorescence intensity of some areas were between normal liver tissues and the lesion,which were suspected to be the marginal zone (which needed to be confirmed by pathology).Three patients (23.1％,3/13) had small lesions on the liver surface,2 were not found by imaging examination,and 1 showed strip calcification on CT.No residual lesions in the liver (except for the microwave ablated lesions) were found after resection.No postoperative complications occurred in all the patients.Seven patients were followed up and no recurrence was found.Conclusions Fluorescence imaging of indocyanine green has the advantages of detecting small and residual lesions in surgery carried out for hepatic alveolar echinococcosis.More studies are needed to confirm the findings.
ABSTRACT
Objective To explore the clinical application of indocyanine green (ICG) fluorescence imaging in patients with hepatocellular carcinoma.Methods 65 hepatocellular carcinoma patients,all were with single lesion,were divided into two groups:preoperative ICG administration group (n =28) and intraoperative ICG administration group (n =37).In preoperative ICG administration group ICG was given 2 to 14 days before surgery,while in the intraoperative ICG administration group it was given during surgery.ICG mediated near-infrared imaging system was used to observe the tumor and determine surgical margin.Results In the preoperative group,tumors were bright fluorescent imaging,in 6 cases 10 new small lesions were found,with cancer diagnosed in 4 patients,cirrhotic liver nodule in 5 patients,fatty degeneration in 1 patient.In the intraoperative group,tumors were clearly demarcated shadow,12 new small lesions were found in 8 cases,with cancer being diagnosed in 5 patients,cirrhotic liver nodule in 4 patients,fatty degeneration in 2 patients,hemangioma in 1 patient.Conclusion Both methods can find small lesions,preoperative administration group was better in identifying the nature of the tumor,while the intraoperative administration group was more valuable in determining the boundaries of the tumor.